Waterfall plot Oncolines™ drug sensitivity

The waterfall plot ranks the 102 cancer cell lines from the Oncolines™ panel on relative sensitivity to dabrafenib in proliferation assays. Cell lines expressing mutant BRAF are indicated in red (all have the V600E mutation, except for BxPC-3); wild type cell lines are indicated in blue.

Hover over the waterfall plot to show the name of each cell line and the IC50 value (in nM).

RKOCOLO 205LS411NSW872RPMI-7951COLO 829G-361DU4475A375ES-25637ACHNBxPC-3A-498A-704DaoyHT-1080AU-565MeWoOVCAR-3769-PDLD-1DU 145HCT 116Hs 578TSW900NCI-H82NCI-H460SW982NCCITT24RS4-11KG-1Jurkat E6.1HCT-15BT-549JARKLECCRF-CEM786-OPA-1DBSRKATO IIIRDA-204TCCSUPVA-ES-BJU-118 MGA-427SU-DHL-6AN3 CAFaDuA-549LNCaP FGCRL95-2SW480HuTu 80SW48SK-N-ASU-87 MGLoVoKU812A-172A388AsPC-1BT-20C-33 ACAL 27CCF-STTG1DoTc2 4510HL-60Hs 746THs 766THTJ82K-562LS 174TMCF7MG-63MIA PaCa-2MOLT-4NCI-H661PC-3PFSK-1RLRT4SHP-77SJCRH30SK-N-FISNU-5SNU-C2BSU-DHL-1SUP-T1SW620SW626SW837T98GTHP-1TTU-2 OS−2−1.5−1−0.500.5
BRAF wild-typeBRAF mutant10logIC​50 - ​10logIC​50, averagedabrafenib
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