Oncolines Team
Oncolines is a precision medicine services company in oncology and cancer immunotherapy. We offer a set of complimentary services to enable our clients to characterize their compounds, determine activities, selectivity, and mechanism of action. Clients are biotech, pharma companies, and academics that seek differentiation for their drugs and drug candidates. Oncolines is a team of higher educated biomedical scientists with a background in pharma, and serves over 100 internationally leading pharmaceutical clients.
Team members
Jorg Benningshof
Jorg Benningshof, Ph.D. – Managing Director
Jorg Benningshof is the Managing Director of Oncolines. He has built a career in the pharmaceutical industry, starting as a research scientist and progressing to Senior Director of Synthetic Chemistry at Symeres. Throughout his career, he has contributed to research and publications in drug discovery and development.
Mandy Smeets
Mandy Smeets, Ph.D. – Investigator
Mandy leads and is involved in several client projects on mechanistic cell biology and immunology. Before joining Oncolines in 2021, Mandy obtained her Ph.D. at the Princess Máxima Center for Pediatric Oncology in Utrecht, studying the role of the bone marrow microenvironment in B-cell leukemia.
Dimitri Pappaioannou
Dimitri Pappaioannou, M.Sc. – Business Developer
Dimitri is responsible for global business development at Oncolines. Prior to Oncolines, he worked at several leading CROs and biotech service providers, such as DiscoveRx, Eurofins, Molecular Probes and Mimetas. Dimitri has a background in molecular biology and a master’s degree from the University of Leiden.
Janneke Melis
Janneke Melis, M.Sc. – Account Manager
Janneke is the first point of contact of clients and manages several projects of returning clients. She studied Biomedical Sciences at Radboud University in Nijmegen and worked in the lab at Oncolines before she moved to her current role.
Jeroen de Roos
Jeroen de Roos, B.Sc. – Senior Investigator
Jeroen leads a team of scientists that perform cancer cell line profiling and combination studies. Jeroen set up the Oncolines cancer cell line panel and developed different formats of drug combination screening known as SynergyFinder. Prior to joining NTRC in 2012, Jeroen worked at Organon/MSD where he led a team responsible for molecular pharmacology testing of Women’s Health, immunology, and receptor target projects. Jeroen studied Biochemistry at the University of Applied Sciences of Rotterdam and worked at the Netherlands Cancer Institute and TNO before joining N.V. Organon in 1997.
Yvonne Grobben
Yvonne Grobben, Ph.D. – Investigator
Yvonne supports client projects in biochemistry and in vivo pharmacology. Before fulfilling her current role, Yvonne obtained her Ph.D. through a collaboration between Oncolines and Utrecht University, studying amino acid-metabolizing enzymes as targets for cancer immunotherapy and treatment of Parkinson’s disease.
Jeffrey Kooijman
Jeffrey Kooijman, M.Sc. – Investigator
Jeffrey developed several bioinformatic algorithms for Oncolines profiling and gene expression analysis. Jeffrey studied biology and bioinformatics at Avans University of Applied Sciences in Breda and the University of Applied Sciences of Nijmegen and Arnhem.
Gerarda van de Kamp
Gerarda van de Kamp, Ph.D. – Investigator
Gerarda leads and contributes to client projects focused on mechanistic cell biology. She joined Oncolines B.V. in 2025 after completing her Ph.D. at the Erasmus Medical Centre in Rotterdam, where she investigated the DNA damage response following proton radiation treatment.