Oncolines™
Helping you to find a mechanistic hypothesis for entering the clinic
Proliferation Assays and Biomarker Discovery
The activity of your compound is determined by proliferation assays on a cancer cell line panel of 102 tumor cell lines. The drug response data are subjected to bioinformatics analysis to help you determine patient stratification markers for clinical trials. We have full commercial licences from the ATCC for use of the cell lines. The bioinformatics analysis is available for proliferation data from the Oncolines™ cancer cell line panel as well as proliferation data that have been generated elsewhere.
Oncolines™ Characteristics
Oncolines™ are proliferation assays
A cancer cell line panel of 102 cell lines
Bioinformatics can be added to find response biomarkers
Bioinformatics analysis is also available for your internal cancer cell line panel data
The Bioinformatics Analysis consists of:
Gene mutation analysis for biomarker discovery
Tissue sensitivity analysis to determine relevant disease areas
Gene expression analysis to identify biological pathways involved in drug sensitivity
Comparative analysis with 160 anti cancer drugs.