AACR-NCI-EORTC Poster A141
Computational models for efficient combination screening

Discovery of Precision Oncology Drugs

NTRC provides in vitro drug discovery services focused on Precision Medicine. We help you to find the informed route to the clinic. Information can be found at www.oncolines.com

Computational Models of Synergy for Efficient Combination Screening

The poster presents three models to predict synergy based on the profiling of single agents in a cancer cell line panel. The model predictions for the PARP inhibitor niraparib are compared to the outcome of a large and unbiased combination screen.

NTRC SYNERGYFINDER™

SYNERGYFINDER™

Combination studies
to identify
novel synergies

NTRC ONCOLINES™

ONCOLINES™

Cancer Cell Line
Proliferation Assays
and Bioinformatics

NTRC Mechanistic Cell Biology

MECHANISTIC CELL BIOLOGY

Cell biology to determine
mechanism of action
of drug candidates

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