AACR-NCI-EORTC Poster B060
Side-by-side comparison of IDO1 inhibitors epacadostat and linrodostat

Side-by-side comparison of small molecule IDO1 inhibitors
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Discovery of Precision Oncology Drugs

NTRC provides in vitro drug discovery services focused on Precision Medicine. We help you to find the informed route to the clinic. Information can be found at www.oncolines.com

Side-by-side comparison of small molecule IDO1 inhibitors

The poster provides a side-by-side comparison of the clinical IDO1 inhibitors epacadostat (INCB024360) and linrodostat (BMS-986205) in biochemical and cell-based assays. The poster also describes the development and validation of a mouse model with two IDO1 inhibitors to evaluate target modulation.

NTRC Mechanistic Cell Biology

MECHANISTIC CELL BIOLOGY

Cell biology to determine
mechanism of action
of drug candidates

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NTRC ONCOLINES™

ONCOLINES™

Cancer Cell Line
Proliferation Assays
and Bioinformatics

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SYNERGYFINDER™

Combination studies
to identify
novel synergies

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