The 28th EORTC-NCI-AACR symposium on Molecular targets and Cancer therapeutics will take place from November 29th to December 2nd, 2016 in Munich, Germany. NTRC will present two posters: one on the application target residence time measurements for protein kinases (ResidenceTimer™), with case studies on PI3 Kinases and Aurora kinases; and one on comparative cancer cell line profiling; the other on comparative cancer cell line profiling (OncolinesProfiler™), with case studies on epigenetic modulators, classic chemotherapeutic agents and protein kinase inhibitors.
Poster titles and sessions:
‘Cell panel profiling of pre-clinical and clinical anti-cancer agents reveals conserved therapeutic clusters and differentiates the mechanism of action of different PI3K/mTOR, Aurora kinase and EZH2 inhibitors’
Presented by Dr. Joost Uitdehaag
Date: Tuesday 29 November
Poster Session: Molecular targeted agents I
Abstract number 52; Poster board number: 023
‘Compound selectivity and target residence time of kinase inhibitors studied with surface plasmon resonance’
Presented by Ms. Nicole Willemsen-Seegers
Date: Wednesday 30 November
Poster Session: Drug Screening
Abstract number: 235; Poster board number: 061.
Information on the technology platform of NTRC can be found at www.ntrc.nl/services.
NTRC facilitates the development of novel therapies by providing cancer cell line profiling services (Oncolines™, SynergyFinder™ and OncolinesProfiler™) and target residence time measurements for protein kinases (ResidenceTimer™) on a fee-for-service basis. NFK GreenScreen™, an assay read-out for the cancer immunotherapy drug targets IDO1 and TDO, is supplied to clients globally. For more information please visit www.ntrc.nl or contact [email protected].