The 25th biannual conference of the European Association of Cancer Research (EACR) with the theme From Fundamental Insight to Rational Cancer Treatment will take place from June 30th to July 2nd in Amsterdam.
NTRC will present 2 posters in the session Experimental/Molecular Therapeutics, Pharmacogenomics:
1. Two-step screening and confirmation approach for synergistic drug combinations
Combination studies with the PARP inhibitor niraparib are presented.
2. Cancer cell line profiling of clinically approved kinase inhibitors for cancer treatment
Case studies show pharmacogenomic analyses for, a.o., the ALK inhibitor brigatinib and the EGFR inhibitor osimertinib.
In addition, a poster on collaborative work between the Radboud University Medical Center (Nijmegen) and NTRC will be presented in the session Translational Research:
3. Prediction of chemotherapy sensitivity on ascites of ovarian cancer patients
The poster describes the work to correlate in vitro characteristics of tumor cells from ascites and clinical results.
The poster presenters are: 1. Martine Prinsen (NTRC), 2. Jeffrey Kooijman (NTRC) and 3. Judith den Ouden (Radboud UMC).