Oss, November, 04, 2019 – NTRC will present a scientific poster at the ELRIG 2019 Drug Discovery Conference ‘Looking Back To The Future’, in Liverpool (UK), November 05-06. The poster is on in vitro screening of primary material and relating this to clinical outcome. The title of the poster is ‘A precision medicine platform to predict the clinical response to chemo- and immunotherapy for epithelial ovarian cancer‘.
Epithelial ovarian cancer (EOC) is the most lethal gynaecologic malignancy. First-line therapy in advanced EOC is surgery in combination with platinum-based chemotherapy and paclitaxel. 15-20% of patients do not respond to this therapy, and in 80% of advanced cases, the disease recurs within three years. Clinical trials with immunotherapies, such as PD-1/PD-L1 blockade, have so far not been successful. There is a need for more diagnostic assays to predict the clinical response to chemo- and immunotherapies. The poster presents a biomarker discovery platform using ascites of ovarian cancer patients.